In this webinar, we will discuss two assays optimized by Eclipsebio to accelerate both academic discoveries and biopharma advancements: eRibo Pro (RiboSeq) to quantitate ribosome occupancy across a transcript, and eSHAPE (SHAPE MaP) chemical probing to accurately predict RNA secondary structure.
Watch the Webinar Recording On-Demand Now!
Webinar Information
About the Webinar
Eclipsebio’s live webinar: Interrogating RNA Structure and Translation Dynamics with SHAPE and Ribosome Profiling, has concluded. Thank you to all the attendees for your participation!
You will learn about the following services we provide:
ㅤeRibo Pro™ | RiboSeq
• Profile ribosome occupancy across an entire transcript.
• Identify genes that are differentially translated.
• Identify upstream (uORF), downstream (dORFs), and non-coding RNA ORFs.
• Identify sites of ribosome stalling and differential codon usage.
Eclipsebio is sole licensee of the Ribo-seq method covered by U.S. Patent Numbers 8,486,865, 9,284,547 and 9,677,068.
ㅤeSHAPE™ | SHAPE MaP
• Chemical probing of RNA to empirically determine secondary structure at single nucleotide resolution.
• Increased RNA structure prediction accuracy over folding algorithms alone.
Eclipsebio is sole licensee of NAI-based RNA structure methods covered by U.S. Patent Numbers 9,428,791 and 11,021,703.
ㅤRBP-eCLIP™ & miR-eCLIP™
• Map miRNAs and RBPs to endogenous and exogenous therapeutic transcripts in cells.
• Map locations of off-target siRNA binding.