RNA Genomics Solutions

Robust next-gen technologies to simplify the complexity of RNA discovery and therapeutic development

Eclipse Bio’s services and kits help overcome the many challenges facing RNA-focused genomics discovery and drug development

Understanding RNA biology

The challenges of gaining a deeper understanding of RNA biology require complex NGS methods to illuminate the molecular mechanisms underlying protein-RNA binding, miRNA targets and RNA modifications

Identify RNA targets

The challenges of identifying highly effective RNA therapeutics require high throughput, robust and NGS methods to comprehensively identify optimal RNA and RNA binding protein targets

Safer RNA drugs

The challenges of developing safe RNA drugs requires highly sensitive, accurate and efficient methods to identify off-target binding

Testimonials

“We approached Eclipse Bio because they were the only company that could perform the robust siRNA off-target binding analysis we needed. They were flexible with our needs and they developed all the experimental and computational tools for our project. Their experimental results provided important additional insights into our own internal findings and were clearly presented in a comprehensive report. Eclipse also provided plenty of helpful post-study support when we had questions or wanted to discuss the data. We look forward to continuing to work with Eclipse Bio in the future”

Alnylam Pharmaceuticals

“My lab had a fantastic experience working with Eclipse Bioinnovations. They made the experiment we sought to do approachable, and the staff was available to help and discuss the project every step of the way.”

Laura D. Attardi, Ph.D., Professor / Stanford University School of Medicine

“As compared to the other CLIP procedures, the eCLIP kit from Eclipse Bioinnovations includes several steps that improves identification of specific protein-nucleic acid interactions.This kit includes almost all necessary reagents as well as a very detailed protocol with essential explanations of the procedure, suggested stop points and potential trouble for each step of the procedure that makes you well prepared for a relatively long protocol, even if you do not have much experience with CLIP techniques. Kit provides sufficient amount of high quality reagents. Importantly, when testing this kit our control sample produced data that was in very good agreement with previously described protein-nucleic acid interactions.In addition, the highly knowledgeable Eclipse customer support scientists were very helpful and provided necessary assistance in clarification of procedure and interpretation of the results.”

Mitchell O'Connell, Ph.D., Assistant Professor / University of Rochester

Some of our recent academic customers

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