What is eCLIP?
Enhanced CrossLinking and Immunoprecipitation (eCLIP), followed by high-throughput sequencing (eCLIP-seq), is a methodology for identifying RNA transcripts bound in vivo by a protein of interest.Learn more about eCLIP
What proteins can be assayed by eCLIP?
To perform eCLIP for a protein of interest, all that is needed is an antibody that can successfully immunoprecipitate the desired protein. We have a pre-validated list of antibodies for 150 proteins, and can provide validation services for additional or custom antibodies.Learn more about validated eCLIP antibodies
What biological samples
can be assayed with eCLIP?
eCLIP can be performed in a wide variety of biological materials, including immortalized cell lines (e.g. HEK293T, K562, HepG2), stem cell and differentiated populations (e.g. ES and IPSC cells, differentiated neuronal precursor cells or neurons) and tissues or organisms (including mouse and human tissues, C. elegans, and more).